Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.47 |
| ▸ | GRM5 | P41594 | 4/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F12 | P00748 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30081026 | 0.85 | MEN1 (0.55) | KDM4ETDP1TGFBR1GRM5NPC1 | |
| SCHEMBL4340551 | 0.82 | KDM4E (0.63) | KDM4ETDP1NPC1RAB9ALMNA | |
| SCHEMBL9487664 | 0.82 | KDM4E (0.50) | KDM4EMAPK14TDP1TGFBR1GRM5 | |
| SCHEMBL1443106 | 0.82 | KDM4E (0.68) | KDM4ETDP1GRM5NPC1RAB9A | |
| SCHEMBL30081031 | 0.81 | TRPV1 (0.54) | KDM4ETDP1NPC1RAB9AMEN1 | |
| SCHEMBL9489482 | 0.79 | KDM4E (0.50) | KDM4EMAPK14TDP1TGFBR1GRM5 | |
| SCHEMBL9487590 | 0.78 | GAA (0.61) | KDM4EMAPK14TDP1GRM5FFAR1 | |
| SCHEMBL29638126 | 0.78 | TGFBR1 (0.57) | KDM4EMAPK14TDP1TGFBR1GRM5 | |
| SCHEMBL1358217 | 0.78 | TGFBR1 (0.57) | KDM4EMAPK14TDP1TGFBR1GRM5 | |
| SCHEMBL4773465 | 0.78 | CYP2A6 (0.63) | KDM4ETDP1GRM5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250533-A | Fungicidal pyridinylpyrimidines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-10-05 | — | — | US | disclosed |
| EP-0431424-A2 | Pyridinylpyrimidin derivatives | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |