Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.96 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.96 |
| ▸ | RAB9A | P51151 | 2/20 | 0.96 |
| ▸ | GAA | P10253 | 1/20 | 0.96 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | TPMT | P51580 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TOP1 | P11387 | 2/20 | 0.57 |
| ▸ | CFD | P00746 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30154503 | 0.98 | TSHR (1.00) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL640263 | 0.98 | TSHR (1.00) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL10541988 | 0.96 | TSHR (0.96) | TSHRALDH1A1KDM4ERAB9AGAA | |
| Hydrochloric Acid SCHEMBL9650466 | 0.96 | TSHR (0.96) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL111732 | 0.89 | TSHR (1.00) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL1560808 | 0.89 | TSHR (0.87) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL10349690 | 0.84 | TSHR (0.75) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL3946244 | 0.84 | TSHR (0.73) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL6550416 | 0.84 | TSHR (0.75) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL9473174 | 0.83 | TSHR (0.73) | TSHRALDH1A1KDM4ERAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189157-A | ANTIBACTERIAL CEPHALOSPORIN COMPOUNDS | HOFFMANN LA ROCHE INC. (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0265185-A2 | Cephalosporins, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-04-27 | — | — | EP | disclosed |