Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | TPMT | P51580 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | TOP1 | P11387 | 2/20 | 0.58 |
| ▸ | CFD | P00746 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30154503 | 1.00 | TSHR (1.00) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL10541988 | 0.98 | TSHR (0.96) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL9489796 | 0.98 | TSHR (0.96) | TSHRALDH1A1KDM4ERAB9AGAA | |
| Hydrochloric Acid SCHEMBL9650466 | 0.98 | TSHR (0.96) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL1560808 | 0.91 | TSHR (0.87) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL111732 | 0.91 | TSHR (1.00) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL10349690 | 0.86 | TSHR (0.75) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL3946244 | 0.86 | TSHR (0.73) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL6550416 | 0.86 | TSHR (0.75) | TSHRALDH1A1KDM4ERAB9AGAA | |
| SCHEMBL9473174 | 0.85 | TSHR (0.73) | TSHRALDH1A1KDM4ERAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893555-B1 | POLYPHENOL-BASED BIOPRECURSOR | RHODIA CHIMIE SA (FR) | 2014-10-29 | — | — | EP | claimed |
| CN-1090756-A | Multipurpose skin-care article | XINHUA INDUSTRY AND TRADE CO L (CN) | 1994-08-17 | — | — | CN | claimed |
| US-4748161-A | Triterpenyl esters of organic acids and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1988-05-31 | — | — | US | claimed |
| EP-0166542-A2 | Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1986-01-02 | — | — | EP | claimed |
| EP-3345910-B1 | COMPOUND HAVING EFFECT OF INHIBITING PLATELET AGGREGATION AND SALT THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING THROMBOTIC DISEASES, CONTAINING SAME | SHIN POONG PHARMACEUTICAL CO LTD (KR) | 2023-11-01 | — | — | EP | disclosed |
| WO-2023166103-A1 | BENZAMIDE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-09-07 | — | — | WO | disclosed |
| CN-111909051-B | N- [ 4-phenyl-3- (benzoylamino) -1, 1-trifluoro-butyl-2-yl ] -phenylalaninol derivative and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2022-12-27 | — | — | CN | disclosed |
| WO-2022255845-A1 | NOVEL ERGOSTENOL DERIVATIVE AND USE THEREOF | 에스티팜 주식회사 | 2022-12-08 | — | — | WO | disclosed |
| US-11414435-B2 | Beta-lactamase inhibitors | VenatoRx Pharmaceuticals, Inc. (US) | 2022-08-16 | — | — | US | disclosed |
| CN-108602837-B | Compound having platelet aggregation inhibitory effect, salt thereof, and composition for preventing or treating thrombotic diseases comprising same | 新丰制药株式会社 | 2022-02-11 | — | — | CN | disclosed |
| CN-111909051-A | N- [ 4-phenyl-3- (benzoylamino) -1,1, 1-trifluoro-butyl-2-yl ] -phenylalaninol derivative and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2020-11-10 | — | — | CN | disclosed |
| US-20200317698-A1 | BETA-LACTAMASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-10-08 | — | — | US | disclosed |
| EP-0178527-A2 | Cephalosporin compounds and process for their preparation | Kaken Pharmaceutical Co., Ltd. (JP) | 1986-04-23 | — | — | EP | disclosed |
| EP-0177596-A1 | BETA-LACTAM DERIVATIVES, PREPARATION, COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1986-04-16 | — | — | EP | disclosed |
| EP-0166542-A2 | Triterpenyl esters of organic acids, process for their production, and hypolipidemic agents composed of them | AMANO PHARMACEUTICAL CO., LTD. (JP) | 1986-01-02 | — | — | EP | disclosed |
| WO-1985004878-A1 | BETA-LACTAM DERIVATIVES, PREPARATION, COMPOSITIONS CONTAINING THEM | BEECHAM GROUP P.L.C. (GB) | 1985-11-07 | — | — | WO | disclosed |
| US-4545942-A | IMMUNOREGULATORS; ANTITUMOR AGENTS | SANKYO COMPANY, LIMITED (JP) | 1985-10-08 | — | — | US | disclosed |
| EP-0115820-A2 | Cephalosporin derivatives and process for their preparation | Kaken Pharmaceutical Co., Ltd. (JP) | 1984-08-15 | — | — | EP | disclosed |
| EP-0082501-A1 | Beta-lactam compound and a pharmaceutical composition containing the same | KYOWA HAKKO KOGYO CO., LTD (JP) | 1983-06-29 | — | — | EP | disclosed |
| EP-0075805-A1 | Beta-lactam compound and a pharmaceutical composition containing the same | KYOWA HAKKO KOGYO CO., LTD (JP) | 1983-04-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200317698-A1 | BETA-LACTAMASE INHIBITORS | MGAM, GAA, LCT | TSHR 4759/4885ALDH1A1 305/4885KDM4E 720/4885 |
| US-11414435-B2 | Beta-lactamase inhibitors | MGAM, GAA, LCT | TSHR 4759/4885ALDH1A1 305/4885KDM4E 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.