Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6297522 | 0.90 | ALDH1A1 (0.56) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| Hydrochloric Acid SCHEMBL28200826 | 0.88 | ALDH1A1 (0.54) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL20808993 | 0.86 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL1799999 | 0.85 | ALDH1A1 (0.84) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL4855526 | 0.85 | ALDH1A1 (0.84) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL4848822 | 0.85 | ALDH1A1 (0.84) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL5479577 | 0.85 | ALDH1A1 (0.84) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL30839396 | 0.85 | ALDH1A1 (0.84) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL1230609 | 0.85 | ALDH1A1 (0.84) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 | |
| SCHEMBL4854620 | 0.85 | ALDH1A1 (0.84) | ALDH1A1HSD17B10HIF1ACYP1B1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5221330-A | Hydrophilic film-forming polymer, buffer, water miscible organic solvent, micelle-forming compound, water | FUJI PHOTO FILM CO., LTD. (JP) | 1993-06-22 | — | — | US | disclosed |