Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15388592 | 0.91 | MAOB (0.49) | MAOBALDH1A1SIGMAR1ADRA2BADRA2C | |
| SCHEMBL8936171 | 0.85 | MAOB (0.51) | MAOBALDH1A1SIGMAR1ADRA2BADRA2C | |
| SCHEMBL8936167 | 0.85 | MAOB (0.51) | MAOBALDH1A1SIGMAR1ADRA2BADRA2C | |
| SCHEMBL8936161 | 0.85 | MAOB (0.51) | MAOBALDH1A1SIGMAR1ADRA2BADRA2C | |
| SCHEMBL8936156 | 0.85 | MAOB (0.51) | MAOBALDH1A1SIGMAR1ADRA2BADRA2C | |
| SCHEMBL25021668 | 0.81 | CARM1 (0.46) | MAOBALDH1A1SIGMAR1ADRA2BADRA2C | |
| SCHEMBL10510837 | 0.81 | MAOB (0.48) | MAOBALDH1A1SIGMAR1ADRA2BADRA2C | |
| SCHEMBL9179252 | 0.79 | TSHR (0.41) | MAOBALDH1A1SIGMAR1ADRA2BADRA2C | |
| SCHEMBL17462349 | 0.79 | TSHR (0.41) | MAOBALDH1A1SIGMAR1ADRA2BADRA2C | |
| SCHEMBL10507207 | 0.77 | MAOB (0.43) | MAOBALDH1A1ADRA2BADRA2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252747-A | Chiral quinolone intermediates | ABBOTT LABORATORIES (US) | 1993-10-12 | — | — | US | disclosed |