⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10043000 | 0.62 | — | — | |
| SCHEMBL4751280 | 0.56 | — | — | |
| SCHEMBL1427438 | 0.56 | — | — | |
| SCHEMBL486270 | 0.54 | — | — | |
| SCHEMBL12179431 | 0.54 | — | — | |
| SCHEMBL18328278 | 0.53 | — | — | |
| SCHEMBL74000 | 0.51 | — | — | |
| SCHEMBL9287418 | 0.50 | — | — | |
| SCHEMBL1081008 | 0.49 | GSK3B (0.43) | — | |
| SCHEMBL32089673 | 0.49 | GSK3B (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557272-A1 | PROCESS FOR THE PREPARATION OF DIFLUOROMALEIC ANHYDRIDE AND INTERMEDIATE COMPOUNDS PRODUCED THEREBY. | DU PONT (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992008710-A1 | PROCESS FOR THE PREPARATION OF DIFLUOROMALEIC ANHYDRIDE AND INTERMEDIATE COMPOUNDS PRODUCED THEREBY | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |