SCHEMBL32089673

SCHEMBL32089673

O=C1NC(=O)c2c(F)ccc(F)c21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.43
GRM5 P41594 2/20 0.42
PPOX P50336 1/20 0.39
CASP3 P42574 2/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CDK2 P24941 3/20 0.37
PARP1 P09874 3/20 0.37
MEN1 O00255 2/20 0.37
PRKD3 O94806 2/20 0.37
PRKCG P05129 2/20 0.37
PRKCB P05771 2/20 0.37
MAPT P10636 2/20 0.37
PRKCA P17252 2/20 0.37
PRKCH P24723 2/20 0.37
PRKCI P41743 2/20 0.37
PRKCE Q02156 2/20 0.37
KMT2A Q03164 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1081008 1.00 GSK3B (0.43) GSK3BGRM5PPOXCASP3CA1
SCHEMBL8274198 0.84 PARP1 (0.40) GSK3BGRM5CASP3CA1CA2
SCHEMBL1080129 0.81 GSK3B (0.52) GSK3BGRM5CASP3CA1CA2
SCHEMBL29578942 0.81 GSK3B (0.52) GSK3BGRM5CASP3CA1CA2
SCHEMBL331905 0.77 TGM2 (0.48) GRM5CASP3CA1CA2CA7
SCHEMBL9279015 0.77 GRM5 (0.46) GSK3BGRM5PPOXCASP3CDK2
SCHEMBL29710128 0.77 GRM5 (0.46) GSK3BGRM5PPOXCASP3CDK2
SCHEMBL28920768 0.75 GRM5 (0.44) GSK3BGRM5PPOXCASP3CDK2
SCHEMBL12425018 0.74 DAO (0.31)
SCHEMBL11548810 0.73 GSK3B (0.43) GSK3BPPOXCASP3CDK2PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4206205-B1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND PRIMEGENE BEIJING CO LTD (CN) 2026-03-04 EP claimed