Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.39 |
| ▸ | F13A1 | P00488 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458613 | 0.91 | P2RX7 (0.63) | P2RX7ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9488219 | 0.91 | P2RX7 (0.63) | P2RX7ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL2456124 | 0.89 | P2RX7 (0.60) | P2RX7ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9489271 | 0.85 | P2RX7 (0.64) | P2RX7ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL2456611 | 0.85 | P2RX7 (0.65) | P2RX7ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9483761 | 0.83 | P2RX7 (0.76) | P2RX7ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9483795 | 0.81 | P2RX7 (0.60) | P2RX7ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9484514 | 0.79 | P2RX7 (0.65) | P2RX7ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9485178 | 0.76 | P2RX7 (0.79) | P2RX7ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9483259 | 0.76 | P2RX7 (0.54) | P2RX7ALDH1A1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245034-A | Compound having vessel smooth muscle relaxation activity | Hidaka, Kiroyoshi (JP) | 1993-09-14 | — | — | US | disclosed |
| US-5216150-A | Muscle relaxant; enzyme inhibitor and platelet aggutination inhibitor | Hidaka, Hiroyoshi (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5081246-A | Isoquinolino sulfonamino derivatives | Hidaka, Hiroyoshi (JP) | 1992-01-14 | — | — | US | disclosed |