Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropyl Alcohol SCHEMBL9451378 | 0.92 | ALDH1A1 (0.43) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL2076979 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL23141274 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL344984 | 0.78 | ALDH1A1 (0.44) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL14538082 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL6259547 | 0.75 | ALDH1A1 (0.60) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| Iodide SCHEMBL6303659 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| Iodide SCHEMBL6303658 | 0.74 | ALDH1A1 (0.58) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL323587 | 0.73 | ALDH1A1 (0.53) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL7363330 | 0.73 | ALDH1A1 (0.53) | ALDH1A1KMT2AKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403185-A2 | Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-19 | — | — | EP | claimed |
| US-5192785-A | Sulfamates as antiglaucoma agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-03-09 | — | — | US | disclosed |