Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.57 |
| ▸ | HTR2A | P28223 | 4/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.57 |
| ▸ | HTR2C | P28335 | 3/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.57 |
| ▸ | HRH1 | P35367 | 3/20 | 0.57 |
| ▸ | DRD3 | P35462 | 3/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.57 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603769 | 0.80 | SLC6A2 (0.58) | SLC6A2HTR2ASLC6A4CHRM1DRD2 | |
| Hydrochloric Acid SCHEMBL7810034 | 0.78 | SLC6A2 (0.59) | SLC6A2HTR2ASLC6A4CHRM1DRD2 | |
| SCHEMBL13808474 | 0.76 | SLC6A4 (0.69) | SLC6A2HTR2ASLC6A4CHRM1DRD2 | |
| SCHEMBL4920568 | 0.76 | SLC6A4 (0.65) | SLC6A2HTR2ASLC6A4CHRM1DRD2 | |
| SCHEMBL22747970 | 0.75 | CYP3A4 (0.53) | SLC6A2HTR2ASLC6A4CHRM1DRD2 | |
| Fumaric Acid SCHEMBL27089596 | 0.74 | CYP3A4 (0.52) | SLC6A2HTR2ASLC6A4CHRM1DRD2 | |
| SCHEMBL9492327 | 0.74 | CHRM2 (0.63) | SLC6A2HTR2ASLC6A4CHRM1DRD2 | |
| SCHEMBL3749292 | 0.74 | HTR2A (0.68) | SLC6A2HTR2ASLC6A4CHRM1DRD2 | |
| SCHEMBL13051501 | 0.74 | HTR2A (0.78) | SLC6A2HTR2ASLC6A4CHRM1DRD2 | |
| SCHEMBL7813757 | 0.74 | SLC6A4 (0.54) | SLC6A2HTR2ASLC6A4CHRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5182387-A | Treatment of malaria | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-01-26 | — | — | US | disclosed |