Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441622 | 0.91 | — | — | |
| SCHEMBL857124 | 0.91 | — | — | |
| SCHEMBL22708 | 0.91 | — | — | |
| SCHEMBL38785 | 0.91 | — | — | |
| SCHEMBL7908923 | 0.89 | KMT2A (0.46) | TRIM24TRIM33THRBCA1CA2 | |
| SCHEMBL22235813 | 0.89 | TRIM24 (0.50) | TRIM24TRIM33THRBCA1CA2 | |
| Cyclohexanone SCHEMBL28845315 | 0.89 | ALDH1A1 (0.50) | TRIM24TRIM33THRBCA1CA2 | |
| Water SCHEMBL28084183 | 0.89 | — | — | |
| SCHEMBL27622 | 0.88 | CA1 (0.60) | TRIM24TRIM33THRBCA1CA2 | |
| SCHEMBL2689503 | 0.86 | TRIM24 (0.50) | TRIM24TRIM33THRBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361673-B1 | COATING COMPOSITIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-17 | — | — | EP | disclosed |
| US-5077379-A | Solvent resistance | ICI PLC (GB) | 1991-12-31 | — | — | US | disclosed |
| EP-0361673-A1 | Coating compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-04-04 | — | — | EP | disclosed |
| US-3951964-A | Method for preparing azines | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-04-20 | — | — | US | disclosed |