SCHEMBL9490796

SCHEMBL9490796

CCCCCCCCCCOc1ccc(CC(O)c2cccc(C(=O)O)c2)nc1/C=C/CO

nearest known ligand 0.83

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 17/20 0.83
PTPN11 Q06124 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9490956 0.91 LTB4R (1.00) LTB4R
SCHEMBL9494461 0.91 LTB4R (1.00) LTB4R
SCHEMBL9491156 0.89 LTB4R (0.66) LTB4RPTPN11
SCHEMBL9490863 0.87 LTB4R (0.64) LTB4R
SCHEMBL9493040 0.82 LTB4R (0.67) LTB4R
SCHEMBL9491463 0.81 LTB4R (0.66) LTB4RPTPN11
SCHEMBL9493086 0.81 LTB4R (1.00) LTB4RPTPN11
SCHEMBL27374038 0.79 LTB4R (0.78) LTB4R
SCHEMBL9494585 0.78 LTB4R (0.64) LTB4RPTPN11
SCHEMBL9491381 0.78 LTB4R (1.00) LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0532634-A1 PHTHALAMIC ACIDS AND THEIR ISOMERS FOR TREATING LEUKOTRIENE-RELATED DISEASES SMITHKLINE BEECHAM CORPORATION (US) 1993-03-24 EP claimed
EP-0532550-A1 BENZOIC ACID DERIVATIVES FOR TREATING LEUKOTRIENE-RELATED DISEASES SMITHKLINE BEECHAM CORPORATION (US) 1993-03-24 EP claimed
WO-1991018880-A1 BENZOIC ACID DERIVATIVES FOR TREATING LEUKOTRIENE-RELATED DISEASES SMITHKLINE BEECHAM CORPORATION (US) 1991-12-12 WO claimed
WO-1991018879-A1 PHTHALAMIC ACIDS AND THEIR ISOMERS FOR TREATING LEUKOTRIENE-RELATED DISEASES SMITHKLINE BEECHAM CORPORATION (US) 1991-12-12 WO claimed