Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 15/20 | 0.43 |
| ▸ | MMP3 | P08254 | 10/20 | 0.43 |
| ▸ | MMP1 | P03956 | 9/20 | 0.43 |
| ▸ | MMP7 | P09237 | 5/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694176 | 0.91 | CSNK1E (0.57) | CSNK1ECNR2MMP2MMP3MMP1 | |
| Hydrogen Sulfide SCHEMBL1149328 | 0.89 | CSNK1E (0.55) | CSNK1ECNR2MMP2MMP3MMP1 | |
| SCHEMBL1149652 | 0.87 | CSNK1E (0.54) | CSNK1ECNR2MMP2MMP3MMP1 | |
| SCHEMBL13283325 | 0.84 | CSNK1E (0.47) | CSNK1ECNR2 | |
| SCHEMBL14937382 | 0.80 | CSNK1E (0.54) | CSNK1ECNR2MMP2MMP3MMP1 | |
| SCHEMBL27838121 | 0.78 | ESR1 (0.55) | CSNK1E | |
| Sulfuric Acid SCHEMBL15752867 | 0.77 | MEN1 (0.57) | — | |
| Sulfuric Acid SCHEMBL17003950 | 0.77 | MEN1 (0.57) | — | |
| Sulfuric Acid SCHEMBL544763 | 0.77 | MEN1 (0.57) | — | |
| Sulfuric Acid SCHEMBL10845199 | 0.77 | MEN1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5192460-A | Carboxylic acid, aminoalkylenephosphonic acid, and phosphoric acid aqueous solution; bathtubs | COLGATE-PALMOLIVE COMPANY (US) | 1993-03-09 | — | — | US | disclosed |