SCHEMBL949113

SCHEMBL949113

FC(F)(F)c1n[c]c(Cl)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5799987 0.74
SCHEMBL5674115 0.70
SCHEMBL19204875 0.69
SCHEMBL156478 0.69 HTT (0.39)
SCHEMBL895450 0.65
SCHEMBL1853978 0.65
SCHEMBL1499272 0.62 TRPV4 (0.35)
SCHEMBL10873933 0.62
SCHEMBL1645145 0.61
SCHEMBL7758168 0.61 PIK3CD (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8299262-B2 Pyridylmethyl-sulfonamide compounds BASF SE (DE) 2012-10-30 US disclosed
EP-2297134-A1 SUBSTITUTED PYRIDIN-4 -YL-METHYL SULFONAMIDES AS FUNGICIDES BASF SE (DE) 2011-03-23 EP disclosed
US-20110065577-A1 Substituted pyridin-4-yl-methyl sulfonamides as fungicides BASF SE (DE) 2011-03-17 US disclosed
US-20110045974-A1 Substituted Triazinylmethyl Sulfonamides BASF SE (DE) 2011-02-24 US disclosed
US-20110003691-A1 Substituted Pyrazinylmethyl Sulfonamides For Use As Fungicides BASF SE (DE) 2011-01-06 US disclosed
EP-2265592-A1 SUBSTITUTED PYRAZ INYLMETHYL SULFONAMIDES FOR USE AS. FUNGICIDES BASF SE (DE) 2010-12-29 EP disclosed
EP-2262794-A1 SULFONAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDE BASF SE (DE) 2010-12-22 EP disclosed
US-20100317516-A1 Sulfonamide Compounds And Their Use As Fungicide BASF SE (DE) 2010-12-16 US disclosed
EP-2252600-A1 SUBSTITUTED TRIAZINYLMETHYL SULFONAMIDES BASF SE (DE) 2010-11-24 EP disclosed
US-20100249077-A1 Pyridylmethyl-Sulfonamide Compounds BASF SE (DE) 2010-09-30 US disclosed
EP-2231605-A1 PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS BASF SE (DE) 2010-09-29 EP disclosed
WO-2009141292-A1 SUBSTITUTED HETEROARYLMETHYL SULFONAMIDES BASF SE (DE) 2009-11-26 WO disclosed
WO-2009141274-A1 SUBSTITUTED PYRIDIN-4 -YL-METHYL SULFONAMIDES AS FUNGICIDES BASF SE (DE) 2009-11-26 WO disclosed
WO-2009112523-A1 SUBSTITUTED PYRAZ INYLMETHYL SULFONAMIDES FOR USE AS. FUNGICIDES BASF SE (DE) 2009-09-17 WO disclosed
WO-2009112533-A1 SUBSTITUTED TRIAZINYLMETHYL SULFONAMIDES BASF SE (DE) 2009-09-17 WO disclosed
WO-2009103650-A1 SULFONAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDE BASF SE (DE) 2009-08-27 WO disclosed
WO-2009071448-A1 PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS BASF SE (DE) 2009-06-11 WO disclosed
WO-2009071449-A1 PYRIDYLMETHYL-SULFONAMIDE COMPOUNDS BASF SE (DE) 2009-06-11 WO disclosed