Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1532600 | 0.82 | TRPA1 (0.48) | MEN1KMT2ATRPA1KDM4EMAPT | |
| SCHEMBL1532602 | 0.82 | TRPA1 (0.48) | MEN1KMT2ATRPA1KDM4EMAPT | |
| SCHEMBL9493051 | 0.79 | MEN1 (0.41) | MEN1KMT2ATRPA1KDM4EMAPT | |
| SCHEMBL10624020 | 0.78 | MEN1 (0.62) | MEN1KMT2AKDM4ELMNAGAA | |
| SCHEMBL4830721 | 0.77 | MEN1 (0.60) | MEN1KMT2AKDM4ELMNAGAA | |
| SCHEMBL3276111 | 0.73 | MEN1 (0.51) | MEN1KMT2ATRPA1HTR2ARELA | |
| SCHEMBL8740782 | 0.73 | MEN1 (0.51) | MEN1KMT2ATRPA1HTR2ARELA | |
| SCHEMBL10708240 | 0.72 | MEN1 (0.55) | MEN1KMT2ATRPA1LMNAGAA | |
| SCHEMBL10708234 | 0.72 | MEN1 (0.55) | MEN1KMT2ATRPA1LMNAGAA | |
| SCHEMBL3320431 | 0.71 | CYP1A2 (0.46) | MEN1KMT2ATRPA1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0229033-B1 | THIOL/ENE COMPOSITIONS | LOCTITE (IRELAND) Ltd. (IE) | 1993-03-03 | — | — | EP | disclosed |
| US-5021512-A | Curable | LOCTITE (IRELAND) LTD. (IE) | 1991-06-04 | — | — | US | disclosed |
| WO-1988002879-A1 | VISIBLE LIGHT CURABLE FREE RADICAL COMPOSITIONS CONTAINING pi-ARENE METAL COMPLEXES | LOCTITE CORPORATION (US) | 1988-04-21 | — | — | WO | disclosed |
| EP-0229033-A2 | Thiol/ene compositions | LOCTITE (IRELAND) Ltd. (IE) | 1987-07-15 | — | — | EP | disclosed |