Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9875263 | 1.00 | HPGD (0.50) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10594984 | 1.00 | HPGD (0.50) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL29445577 | 0.94 | HPGD (0.43) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9489704 | 0.94 | HPGD (0.43) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9874727 | 0.94 | HPGD (0.43) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10592860 | 0.89 | GAA (0.48) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL5256942 | 0.89 | GAA (0.48) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9492350 | 0.89 | GAA (0.48) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9874165 | 0.88 | HPGD (0.38) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9490077 | 0.88 | HPGD (0.38) | HPGDGAASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342849-A2 | Intermediates for preparing 1,4-dihydro-4-oxo-quinoline-3-carboxylic acid esters | PFIZER INC. (US) | 1989-11-23 | — | — | EP | claimed |
| EP-0345464-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED 3-AMINO-2-(BENZOYL)ACRYLIC ACID ESTERS AS WELL AS A PROCESS FOR THE PREPARATION OF INTERMEDIATES FOR ANTIBACTERIAL ACTIVE AGENTS FROM THESE COMPOUNDS | Chemie Linz Gesellschaft m.b.H. (AT) | 1993-03-17 | — | — | EP | disclosed |
| US-5011971-A | Process for the preparation of substituted 3-amino-2 (benzoyl)-acrylic acid esters, and a process for the preparation of intermediates for antibacterial active compounds from these compounds | CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) | 1991-04-30 | — | — | US | disclosed |
| EP-0345464-A2 | Process for the preparation of substituted 3-amino-2-(benzoyl)acrylic acid esters as well as a process for the preparation of intermediates for antibacterial active agents from these compounds | Chemie Linz Gesellschaft m.b.H. (AT) | 1989-12-13 | — | — | EP | disclosed |
| EP-0342849-A2 | Intermediates for preparing 1,4-dihydro-4-oxo-quinoline-3-carboxylic acid esters | PFIZER INC. (US) | 1989-11-23 | — | — | EP | disclosed |