Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445577 | 1.00 | HPGD (0.43) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9489704 | 1.00 | HPGD (0.43) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9491280 | 0.94 | HPGD (0.50) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9875263 | 0.94 | HPGD (0.50) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10594984 | 0.94 | HPGD (0.50) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9211517 | 0.90 | GAA (0.42) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9562462 | 0.90 | GAA (0.42) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9720579 | 0.90 | GAA (0.42) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL10456009 | 0.90 | HPGD (0.38) | HPGDGAASMN1; SMN2NPC1RAB9A | |
| SCHEMBL29754269 | 0.90 | GAA (0.42) | HPGDGAASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011971-A | Process for the preparation of substituted 3-amino-2 (benzoyl)-acrylic acid esters, and a process for the preparation of intermediates for antibacterial active compounds from these compounds | CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) | 1991-04-30 | — | — | US | disclosed |
| US-4699992-A | 3-amino-2-benzoylacrylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-13 | — | — | US | disclosed |