SCHEMBL9491335

SCHEMBL9491335

NNC(=S)SCSC(=S)NN

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
PTGS2 P35354 1/20 0.37
HSD17B10 Q99714 1/20 0.37
PHGDH O43175 1/20 0.31
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9737802 0.77
SCHEMBL7068168 0.71
SCHEMBL11175493 0.69
SCHEMBL11033622 0.69 ALDH1A1 (0.44) ALDH1A1PTGS2HSD17B10PHGDH
SCHEMBL2321194 0.68 HTT (0.41) ALDH1A1HSD17B10MGLL
Hydrazine SCHEMBL11634157 0.67 ALDH1A1 (0.41) ALDH1A1PTGS2HSD17B10
SCHEMBL6210141 0.65 CA12 (0.55)
SCHEMBL28293833 0.65
SCHEMBL11033624 0.65
SCHEMBL28797073 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0403524-B1 PREPARATION OF NITRURO COMPOUNDS USABLE AS RADIO-PHARMACEUTICAL PRODUCTS CIS BIO INTERNATIONAL (FR) 1993-02-10 EP claimed