SCHEMBL949138

SCHEMBL949138

C1=CC2CCC1C2.CC[Si](C)(C)OCC1CO1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 2/20 0.33
MAPK1 P28482 1/20 0.31
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27796619 0.77 TSHR (0.39) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL27881385 0.75 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL949194 0.74
SCHEMBL27865191 0.73 SMN1; SMN2 (0.73) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL27865175 0.72 TSHR (0.35) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL23202820 0.72 SMN1; SMN2 (0.33) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL27881386 0.71 ALDH1A1 (0.75) SMN1; SMN2ALDH1A1TDP1TSHR
SCHEMBL27881383 0.70 TSHR (0.41) SMN1; SMN2ALDH1A1TDP1TSHRMAPK1
SCHEMBL12910915 0.68 ALDH1A1 (0.34) ALDH1A1
SCHEMBL17775092 0.68 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7875686-B2 comprising 10 to 99 wt. % of norbornene-type cycloolefin monomers; for microelectronic, optoelectronic and micro-optoelectronic applications such as die attach adhesives, underfill materials, prepreg binders, encapsulants PROMERUS LLC (US) 2011-01-25 US disclosed
EP-1791888-B1 POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS PROMERUS LLC (US) 2009-03-25 EP disclosed
EP-1791888-A1 POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS Promerus, LLC (US) 2007-06-06 EP disclosed
WO-2006023511-A1 POLYCYCLOOLEFIN POLYMERIC COMPOSITIONS FOR SEMICONDUCTOR APPLICATIONS PROMERUS LLC (US) 2006-03-02 WO disclosed
US-20060041093-A1 Polycycloolefin polymeric compositions for semiconductor applications SUMITOMO BAKELITE CO., LTD. (JP) 2006-02-23 US disclosed