Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 20/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 8/20 | 1.00 |
| ▸ | NQO2 | P16083 | 2/20 | 0.78 |
| ▸ | HTR2C | P28335 | 1/20 | 0.68 |
| ▸ | HTR2B | P41595 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492088 | 0.99 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL5929464 | 0.97 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL6247137 | 0.94 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL29493844 | 0.94 | MTNR1A (1.00) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL8021679 | 0.88 | MTNR1A (0.87) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL8858577 | 0.87 | MTNR1A (0.77) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL8858486 | 0.86 | MTNR1A (0.79) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL25029641 | 0.85 | MTNR1A (0.75) | MTNR1AMTNR1BNQO2HTR2CHTR2B | |
| SCHEMBL8961302 | 0.84 | MTNR1A (0.90) | MTNR1AMTNR1BNQO2HTR2C | |
| SCHEMBL8961097 | 0.84 | MTNR1A (0.90) | MTNR1AMTNR1BNQO2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225442-A | Melatoninergic disorders | ADIR ET COMPAGNIE (FR) | 1993-07-06 | — | — | US | disclosed |
| US-5194614-A | COMPOUNDS HAVING A NAPHTHALENE STRUCTURE | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |