⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29165313 | 0.97 | ALDH1A1 (0.69) | — | |
| SCHEMBL896593 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL19922527 | 0.87 | — | — | |
| Iodide SCHEMBL296056 | 0.87 | — | — | |
| SCHEMBL21216 | 0.82 | ALDH1A1 (0.91) | — | |
| Hydrochloric Acid SCHEMBL10934116 | 0.78 | ALDH1A1 (0.83) | — | |
| SCHEMBL1729138 | 0.78 | ALDH1A1 (1.00) | — | |
| SCHEMBL7942101 | 0.78 | ALDH1A1 (1.00) | — | |
| SCHEMBL35856 | 0.78 | ALDH1A1 (1.00) | — | |
| SCHEMBL235238 | 0.78 | ALDH1A1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11785845-B2 | Composition | FUJIFILM CORPORATION (JP) | 2023-10-10 | — | — | US | disclosed |
| WO-2023116761-A1 | PYRIMIDINE HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 英矽智能科技知识产权有限公司 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023119098-A1 | PROTEIN KINASE C THETA INHIBITORS | Galderma Holding SA (CH) | 2023-06-29 | — | — | WO | disclosed |
| EP-3405477-B1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| US-11566022-B2 | 3-(5-methoxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | NOVARTIS AG (CH) | 2023-01-31 | — | — | US | disclosed |
| WO-2023275337-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-01-05 | — | — | WO | disclosed |
| WO-2023275333-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-01-05 | — | — | WO | disclosed |
| US-20220389016-A1 | COMPOUND AND METHOD FOR PRODUCING COMPOUND | FUJIFILM CORPORATION (JP) | 2022-12-08 | — | — | US | disclosed |
| US-20220045283-A1 | COMPOSITION | FUJIFILM CORPORATION (JP) | 2022-02-10 | — | — | US | disclosed |
| EP-3568391-B1 | BENZENE DISULFONAMIDE FOR THE TREATMENT OF CANCER | MAX PLANCK GESELLSCHAFT (DE) | 2020-11-11 | — | — | EP | disclosed |
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |
| EP-3357904-A1 | CHIRAL DIACHYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | Intrexon Corporation (US) | 2018-08-08 | — | — | EP | disclosed |
| EP-3351544-A1 | BENZENE DISULFONAMIDE FOR THE TREATMENT OF CANCER | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2018-07-25 | — | — | EP | disclosed |
| WO-2018130625-A1 | BENZENE DISULFONAMIDE FOR THE TREATMENT OF CANCER | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2018-07-19 | — | — | WO | disclosed |
| WO-2018122419-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2018-07-05 | — | — | WO | disclosed |
| EP-3342779-A1 | INHIBITORS OF TRANSGLUTAMINASES | Zedira GmbH (DE) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017041701-A1 | NITRIC OXIDE-RELEASING PRODRUG MOLECULE | 浙江华海药业股份有限公司 | 2017-03-16 | — | — | WO | disclosed |
| WO-2016203112-A1 | SPIRO[CYCLOBUTANE-1,3'-INDOLIN]-2'-ONE DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORPORATION (FI) | 2016-12-22 | — | — | WO | disclosed |
| US-5256651-A | Thickeners for subterranean formation fracturing fluids | RHONE-POULENC, INC. (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0496584-A2 | Hydrophilic-Hydrophobic derivatives of polygalactomannans containing tertiary amine functionality | STEIN, HALL & CO., INC. (US) | 1992-07-29 | — | — | EP | disclosed |