Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 13/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 12/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 12/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 12/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 11/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 11/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 9/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363816 | 0.85 | ITGB3 (0.46) | ITGB3ITGA2BGABRA5GABRA1GABRG2 | |
| SCHEMBL7327746 | 0.83 | ITGB3 (0.48) | ITGB3ITGA2BGABRA5GABRA1GABRG2 | |
| SCHEMBL7331758 | 0.80 | ITGB3 (0.46) | ITGB3ITGA2BGABRA5GABRA1GABRG2 | |
| SCHEMBL7321185 | 0.78 | ITGB3 (0.52) | ITGB3ITGA2BGABRA5GABRA1GABRG2 | |
| SCHEMBL7330261 | 0.77 | ITGB3 (0.55) | ITGB3ITGA2BGABRA5GABRA1GABRG2 | |
| SCHEMBL7331776 | 0.77 | ITGB3 (0.57) | ITGB3ITGA2BGABRA5GABRA1GABRG2 | |
| SCHEMBL7332398 | 0.77 | ITGB3 (0.39) | ITGB3ITGA2BGABRA5GABRA1GABRG2 | |
| SCHEMBL9009458 | 0.76 | ITGB3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL7329148 | 0.76 | ITGB3 (0.40) | ITGB3ITGA2BGABRA5GABRA1GABRG2 | |
| SCHEMBL7330636 | 0.75 | ITGB3 (0.39) | ITGB3ITGA2BGABRA5GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250679-A | Nonpeptidyl platelet aggregation inhibitors having specificity for the GPIIb III.sub. receptor | GENENTECH, INC. (US) | 1993-10-05 | — | — | US | disclosed |