Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492294 | 1.00 | HPGD (0.35) | HPGDSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL9494147 | 0.96 | HPGD (0.33) | HPGDSMN1; SMN2LMNAMAPTCYP1A2 | |
| SCHEMBL9494145 | 0.96 | HPGD (0.33) | HPGDSMN1; SMN2LMNAMAPTCYP1A2 | |
| SCHEMBL9492161 | 0.94 | HPGD (0.37) | HPGDSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL9492159 | 0.94 | HPGD (0.37) | HPGDSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL9422452 | 0.91 | HPGD (0.37) | HPGDSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL9493042 | 0.91 | HPGD (0.37) | HPGDSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL9493857 | 0.91 | HPGD (0.36) | HPGDSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL9493861 | 0.91 | HPGD (0.36) | HPGDSMN1; SMN2LMNAMAPTALDH1A1 | |
| SCHEMBL9491324 | 0.86 | HPGD (0.39) | HPGDSMN1; SMN2LMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5229514-A | Thiourea compounds containing pyridazine ring | CIBA-GEIGY CORPORATION (US) | 1993-07-20 | — | — | US | disclosed |
| US-5135562-A | 8-thia-1,6-diazabicyclo[4.3.0]nonane herbicides | CIBA-GEIGY CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |