Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842900 | 0.94 | KMT2A (0.55) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| Oxalic Acid SCHEMBL9495879 | 0.93 | KMT2A (0.49) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL9492980 | 0.85 | KMT2A (0.55) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL8988266 | 0.82 | KMT2A (0.56) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| SCHEMBL9492485 | 0.80 | KDM4E (0.38) | KMT2AKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL7759295 | 0.76 | KMT2A (0.53) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| Oxalic Acid SCHEMBL9492098 | 0.76 | KMT2A (0.60) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| Oxalic Acid SCHEMBL9494625 | 0.75 | CHRM1 (0.54) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| Oxalic Acid SCHEMBL9491522 | 0.74 | CHRM1 (0.51) | KMT2ACHRM1CHRM2CHRM4CHRM5 | |
| Oxalic Acid SCHEMBL9492215 | 0.73 | KMT2A (0.49) | KMT2ACHRM1CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177084-A | 1-Azabicycles, Treating Mental Disorders | MERCK SHARP & DOHME LTD. (GB) | 1993-01-05 | — | — | US | disclosed |
| EP-0412797-A2 | The therapeutic use of substituted benzenes, formulations thereof and novel substituted benzenes | MERCK SHARP & DOHME LTD. (GB) | 1991-02-13 | — | — | EP | disclosed |