Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | RPLP1 | P05386 | 5/20 | 0.38 |
| ▸ | RPLP0 | P05388 | 5/20 | 0.38 |
| ▸ | RPS17 | P08708 | 5/20 | 0.38 |
| ▸ | RPSA | P08865 | 5/20 | 0.38 |
| ▸ | RPS2 | P15880 | 5/20 | 0.38 |
| ▸ | RPL35A | P18077 | 5/20 | 0.38 |
| ▸ | RPL7 | P18124 | 5/20 | 0.38 |
| ▸ | RPL17 | P18621 | 5/20 | 0.38 |
| ▸ | RPS4Y1 | P22090 | 5/20 | 0.38 |
| ▸ | RPS3 | P23396 | 5/20 | 0.38 |
| ▸ | RPS12 | P25398 | 5/20 | 0.38 |
| ▸ | RPL13 | P26373 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL948779 | 1.00 | CHRM2 (0.44) | CHRM2CHRM3KCNH2SLC6A2SLC6A4 | |
| SCHEMBL948777 | 1.00 | CHRM2 (0.44) | CHRM2CHRM3KCNH2SLC6A2SLC6A4 | |
| SCHEMBL949634 | 0.86 | SLC6A4 (0.44) | KCNH2SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL948516 | 0.86 | SLC6A4 (0.44) | KCNH2SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL948515 | 0.86 | SLC6A4 (0.44) | KCNH2SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL949410 | 0.83 | SLC6A4 (0.48) | KCNH2SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL948457 | 0.83 | SLC6A4 (0.48) | KCNH2SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL948455 | 0.83 | SLC6A4 (0.48) | KCNH2SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL17440453 | 0.83 | RPLP1 (0.44) | KCNH2SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL12614459 | 0.80 | CHRM3 (0.52) | CHRM2CHRM3KCNH2HRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110021569-A1 | Piperidine compounds, a process for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER, UNIVERSITE (FR) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021569-A1 | Piperidine compounds, a process for their preparation and pharmaceutical compositions containing them | BDNF, GRIN2C, GRIN2A | CHRM2 22/4885CHRM3 96/4885KCNH2 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.