Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16216287 | 0.88 | KDM4E (0.54) | SMN1; SMN2APPMEN1KMT2AALDH1A1 | |
| SCHEMBL13567551 | 0.88 | KDM4E (0.54) | SMN1; SMN2APPMEN1KMT2AALDH1A1 | |
| SCHEMBL17694760 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2PSMB1PSMB5PSMB2MEN1 | |
| SCHEMBL79031 | 0.83 | SMN1; SMN2 (0.68) | SMN1; SMN2PSMB1PSMB5PSMB2MEN1 | |
| SCHEMBL10883892 | 0.83 | SMN1; SMN2 (0.83) | SMN1; SMN2PSMB1PSMB5PSMB2MEN1 | |
| SCHEMBL9818198 | 0.83 | SMN1; SMN2 (0.68) | SMN1; SMN2PSMB1PSMB5PSMB2MEN1 | |
| SCHEMBL10457449 | 0.82 | APP (0.59) | APPALDH1A1 | |
| SCHEMBL9618310 | 0.82 | SMN1; SMN2 (0.69) | SMN1; SMN2PSMB1PSMB5PSMB2MEN1 | |
| SCHEMBL17912 | 0.82 | KDM4E (0.56) | SMN1; SMN2PSMB1PSMB5PSMB2MEN1 | |
| SCHEMBL4738149 | 0.81 | SMN1; SMN2 (0.58) | SMN1; SMN2PSMB1PSMB5PSMB2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347227-B1 | Pesticidal compositions | DU PONT (US) | 1993-11-24 | — | — | EP | disclosed |
| US-5232484-A | Aqueous acid solution; mineralization; absence of large concentrations of organic solvents, chloride and sulfate | THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION (US) | 1993-08-03 | — | — | US | disclosed |
| US-5135744-A | PALATABLE SOLID PESTICIDAL COMPOSITIONS OF ETHYLENE AND VINYL ACETATE COPOLYMER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0347227-A1 | Pesticidal compositions | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-12-20 | — | — | EP | disclosed |