Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712455 | 1.00 | IDO1 (0.55) | IDO1PAMALOX5SIGMAR1HTR2A | |
| SCHEMBL4456215 | 0.96 | IDO1 (0.52) | IDO1PAMALOX5SIGMAR1HTR2A | |
| SCHEMBL7768646 | 0.89 | IDO1 (0.52) | IDO1PAMALOX5SIGMAR1HTR2A | |
| SCHEMBL3438761 | 0.89 | IDO1 (0.52) | IDO1PAMALOX5SIGMAR1HTR2A | |
| SCHEMBL7768636 | 0.87 | IDO1 (0.50) | IDO1PAMALOX5SIGMAR1HTR2A | |
| SCHEMBL8734900 | 0.84 | IDO1 (0.59) | IDO1PAMALOX5SIGMAR1HTR2A | |
| SCHEMBL29154660 | 0.84 | IDO1 (0.59) | IDO1PAMALOX5SIGMAR1HTR2A | |
| SCHEMBL430935 | 0.83 | IDO1 (0.68) | IDO1PAMSIGMAR1HTR2AHTR2C | |
| SCHEMBL7514298 | 0.83 | IDO1 (0.68) | IDO1PAMSIGMAR1HTR2AHTR2C | |
| SCHEMBL430934 | 0.83 | IDO1 (0.68) | IDO1PAMSIGMAR1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0229033-B1 | THIOL/ENE COMPOSITIONS | LOCTITE (IRELAND) Ltd. (IE) | 1993-03-03 | — | — | EP | disclosed |
| US-5137889-A | Hypotensive agents; coronary vasodilators; calcium antagonists; antiinflammatory agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-11 | — | — | US | disclosed |
| US-5034395-A | Hypotensive agents, carboxylated dihydropyridines | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| US-5021512-A | Curable | LOCTITE (IRELAND) LTD. (IE) | 1991-06-04 | — | — | US | disclosed |
| EP-0229033-A2 | Thiol/ene compositions | LOCTITE (IRELAND) Ltd. (IE) | 1987-07-15 | — | — | EP | disclosed |