SCHEMBL430934

SCHEMBL430934

C(=C/c1ccccc1)\COC/C=C/c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.68
HTR2A P28223 6/20 0.50
SIGMAR1 Q99720 4/20 0.50
HTR2C P28335 3/20 0.50
HTR2B P41595 3/20 0.50
PAM P19021 1/20 0.50
MAOB P27338 1/20 0.48
DRD2 P14416 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7514298 1.00 IDO1 (0.68) IDO1HTR2ASIGMAR1HTR2CHTR2B
SCHEMBL430935 1.00 IDO1 (0.68) IDO1HTR2ASIGMAR1HTR2CHTR2B
SCHEMBL7254873 0.91 IDO1 (0.63) IDO1HTR2ASIGMAR1HTR2CHTR2B
SCHEMBL7254870 0.91 IDO1 (0.63) IDO1HTR2ASIGMAR1HTR2CHTR2B
SCHEMBL20127256 0.91 IDO1 (0.63) IDO1HTR2ASIGMAR1HTR2CHTR2B
Catechol SCHEMBL10615010 0.89 IDO1 (0.57) IDO1HTR2ASIGMAR1HTR2CHTR2B
SCHEMBL1158122 0.89 IDO1 (0.57) IDO1HTR2ASIGMAR1HTR2CHTR2B
Catechol SCHEMBL10615001 0.89 IDO1 (0.57) IDO1HTR2ASIGMAR1HTR2CHTR2B
SCHEMBL1158123 0.89 IDO1 (0.57) IDO1HTR2ASIGMAR1HTR2CHTR2B
SCHEMBL10624030 0.89 IDO1 (0.62) IDO1HTR2ASIGMAR1HTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024119101-A1 STIMULI-RESPONSIVE TRACELESS ENGINEERING PLATFORM FOR INTRACELLULAR PAYLOAD DELIVERY YALE UNIVERSITY (US) 2024-06-06 WO claimed
US-8308892-B2 Di-cinnamyl compounds and methods for use thereof DESIGNER MOLECULES, INC. (US) 2012-11-13 US claimed
US-20090288768-A1 DI-CINNAMYL COMPOUNDS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. 2009-11-26 US claimed
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION FIRMENICH & CIE (CH) 2026-03-12 US disclosed
CN-121591684-A Regulation and control method for catalyzing transfer hydrogenation and etherification of biomass-based aldehydes 岭南师范学院 2026-03-03 CN disclosed
US-RE50800-E1 Pro-fragrance compounds FIRMENICH SA (CH) 2026-02-17 US disclosed
EP-4604951-A1 1-(SULFONYL)-N-PHENYLPYRROLIDINE-2-CARBOXAMIDES DERIVATIVES AND USE THEREOF AMIRA THERAPEUTICS, S.L. (ES) 2025-08-27 EP disclosed
US-12264295-B2 Encapsulated pro-perfume compounds FIRMENICH SA (CH) 2025-04-01 US disclosed
US-20240350381-A1 FRAGRANCES WITH IMPROVED LONG-LASTING PERFORMANCE FIRMENICH SA (CH) 2024-10-24 US disclosed
CN-115480016-B Liquid chromatographic analysis and detection method of laurinol polyoxyethylene ether nonionic surfactant 中国科学院兰州化学物理研究所 2024-09-17 CN disclosed
CN-118638826-A Application of surfactant or nano-disc in synthesizing membrane protein in cell-free synthesis system 清华大学 2024-09-13 CN disclosed
US-4839325-A FLUORINATED, 2,4 PENTADIONE AND FATTY ACID METAL SALT; INCREASED POT LIFE MONSANTO COMPANY (US) 1989-06-13 US disclosed
US-4826923-A Allyloxy activated surface coatings MONSANTO COMPANY (US) 1989-05-02 US disclosed
US-4816535-A FREE RADICAL-POLYMERIZABLE COMPOUND, FUGITIVE ACID-STABILIZED METAL DRIER AND PEROXIDE INITIATOR MONSANTO COMPANY (US) 1989-03-28 US disclosed
US-4810757-A MODERATED METAL DRIER MONSANTO COMPANY (US) 1989-03-07 US disclosed
EP-0296141-A2 Allyloxy activated surface coatings Monsanto Company (US) 1988-12-21 EP disclosed
EP-0296140-A2 Allyloxy-activated surface coatings Monsanto Company (US) 1988-12-21 EP disclosed
EP-0273025-A2 Stabilized metal drier MONSANTO COMPANY (US) 1988-06-29 EP disclosed
US-4670308-A FREE RADICAL POLYMERIZATION MONSANTO COMPANY (US) 1987-06-02 US disclosed
EP-0210158-A1 Surface coating process Monsanto Company (US) 1987-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION CNOT9, MSL1, MT-CO2 IDO1 638/4885HTR2A 2456/4885SIGMAR1 1863/4885
US-20240350381-A1 FRAGRANCES WITH IMPROVED LONG-LASTING PERFORMANCE FABP5, FAAH2, FASN IDO1 867/4885HTR2A 585/4885SIGMAR1 253/4885
US-20090288768-A1 DI-CINNAMYL COMPOUNDS AND METHODS FOR USE THEREOF CAD, DBF4, ACMSD IDO1 2736/4885HTR2A 4135/4885SIGMAR1 4142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.