Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492868 | 1.00 | CYP3A4 (0.46) | CYP3A4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL8841067 | 0.80 | AKR1C3 (0.53) | CYP3A4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL4624146 | 0.79 | MEN1 (0.61) | MEN1KMT2AKDM4ELMNAMAPT | |
| SCHEMBL11447957 | 0.78 | CYP3A4 (0.46) | CYP3A4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL10476860 | 0.77 | KMT2A (0.59) | CYP3A4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL10476862 | 0.77 | KMT2A (0.59) | CYP3A4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL5533756 | 0.76 | CYP3A4 (0.44) | CYP3A4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL8219793 | 0.76 | MEN1 (0.64) | CYP3A4MEN1KMT2AKDM4ELMNA | |
| SCHEMBL1554123 | 0.76 | ALDH1A1 (0.55) | CYP3A4MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL7024675 | 0.75 | CYP3A4 (0.51) | CYP3A4MEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0229033-B1 | THIOL/ENE COMPOSITIONS | LOCTITE (IRELAND) Ltd. (IE) | 1993-03-03 | — | — | EP | disclosed |
| US-5021512-A | Curable | LOCTITE (IRELAND) LTD. (IE) | 1991-06-04 | — | — | US | disclosed |
| EP-0229033-A2 | Thiol/ene compositions | LOCTITE (IRELAND) Ltd. (IE) | 1987-07-15 | — | — | EP | disclosed |