Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820670 | 0.88 | CYP11B2 (0.46) | CYP11B2MAPK1CYP11B1ADAMTS5IDO1 | |
| SCHEMBL2820626 | 0.88 | CYP11B2 (0.46) | CYP11B2MAPK1CYP11B1ADAMTS5IDO1 | |
| SCHEMBL2820579 | 0.88 | CYP11B2 (0.46) | CYP11B2MAPK1CYP11B1ADAMTS5IDO1 | |
| SCHEMBL13475345 | 0.88 | CYP11B2 (0.46) | CYP11B2MAPK1CYP11B1ADAMTS5IDO1 | |
| SCHEMBL2817732 | 0.88 | CYP11B2 (0.46) | CYP11B2MAPK1CYP11B1ADAMTS5IDO1 | |
| SCHEMBL2819153 | 0.87 | CYP11B2 (0.45) | CYP11B2MAPK1CYP11B1ADAMTS5IDO1 | |
| SCHEMBL13475349 | 0.87 | CYP11B2 (0.45) | CYP11B2MAPK1CYP11B1ADAMTS5IDO1 | |
| SCHEMBL2818042 | 0.87 | CYP11B2 (0.45) | CYP11B2MAPK1CYP11B1ADAMTS5IDO1 | |
| SCHEMBL13475350 | 0.87 | CYP11B2 (0.45) | CYP11B2MAPK1CYP11B1ADAMTS5IDO1 | |
| SCHEMBL9777311 | 0.84 | CYP11B2 (0.43) | CYP11B2MAPK1CYP11B1ADAMTS5IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246915-A | Herbicides | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-09-21 | — | — | US | disclosed |