Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494350 | 1.00 | MEN1 (0.64) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL15132047 | 0.90 | MEN1 (0.76) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL9361425 | 0.90 | MEN1 (0.76) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL9361429 | 0.90 | MEN1 (0.76) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL9361387 | 0.85 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL9360759 | 0.85 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL11988543 | 0.84 | MEN1 (0.67) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL21160479 | 0.84 | CISD1 (0.55) | ALDH1A1EGFRCISD1KDM4ESLC16A3 | |
| SCHEMBL15138659 | 0.83 | MEN1 (0.62) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL22954004 | 0.83 | SLC16A3 (0.64) | MEN1KMT2AALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212269-A | Main chain chromophoric polymers with second order nonlinear optical properties | UNITED STATES OF AMERICA, THE, AS REPRESENTED BY THE SECRETARY OF THE NAVY | 1993-05-18 | — | — | US | disclosed |