Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.46 |
| ▸ | RARB | P10826 | 4/20 | 0.45 |
| ▸ | MPL | P40238 | 4/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9492798 | 0.98 | HDAC3 (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL20343303 | 0.95 | HDAC3 (0.49) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7786808 | 0.95 | HDAC3 (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7788958 | 0.94 | RARB (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8987882 | 0.94 | HDAC3 (0.50) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9563700 | 0.94 | HDAC3 (0.50) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9497689 | 0.94 | RARB (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9497766 | 0.94 | RARB (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7790562 | 0.94 | RARB (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9496656 | 0.94 | RARB (0.52) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980129-B2 | Liquid-crystal compound with negative dielectric anisotropy, liquid-crystal display, and optoelectronic device | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2015-03-17 | — | — | US | disclosed |
| US-8980129-B2 | Liquid-crystal compound with negative dielectric anisotropy, liquid-crystal display, and optoelectronic device | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2015-03-17 | — | — | US | disclosed |
| US-5273680-A | A chiral tilted smectic liquid crystal based on terphenyls | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-12-28 | — | — | US | disclosed |
| EP-0329752-B1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK PATENT GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0329752-A1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK PATENT GmbH (DE) | 1989-08-30 | — | — | EP | disclosed |