Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3173146 | 0.77 | TDP1 (0.38) | ALDH1A1TDP1MEN1KMT2AMAPT | |
| SCHEMBL24257818 | 0.77 | TDP1 (0.39) | ALDH1A1TDP1MEN1KMT2AGRIN2D | |
| SCHEMBL30632569 | 0.77 | TDP1 (0.39) | ALDH1A1TDP1MEN1KMT2AGRIN2D | |
| SCHEMBL27641088 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TDP1MEN1KMT2AGRIN2D | |
| SCHEMBL29892635 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TDP1MEN1KMT2AGRIN2D | |
| SCHEMBL5216651 | 0.76 | ALDH1A1 (0.43) | ALDH1A1TDP1MEN1KMT2AGRIN2D | |
| SCHEMBL29735712 | 0.74 | ALDH1A1 (0.42) | ALDH1A1TDP1MEN1KMT2AGRIN2D | |
| SCHEMBL20679540 | 0.73 | ALDH1A1 (0.37) | ALDH1A1TDP1MAPTKDM4ETSHR | |
| SCHEMBL13480742 | 0.73 | CCR1 (0.38) | ALDH1A1KDM4ETSHRPOLB | |
| SCHEMBL8194928 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TDP1MEN1KMT2AGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3215472-A | — | — | None | — | — | JP | disclosed |
| US-10005721-B2 | Dimethylbenzoic acid compounds | ELI LILLY AND COMPANY (US) | 2018-06-26 | — | — | US | disclosed |
| US-10005721-B2 | Dimethylbenzoic acid compounds | ELI LILLY AND COMPANY (US) | 2018-06-26 | — | — | US | disclosed |
| CN-105793236-B | Dimethylbenzoic acid compound | 伊莱利利公司 | 2017-10-10 | — | — | CN | disclosed |
| EP-3083554-A1 | DIMETHYLBENZOIC ACID COMPOUNDS | Eli Lilly & Company (US) | 2016-10-26 | — | — | EP | disclosed |
| US-20160251306-A1 | DIMETHYLBENZOIC ACID COMPOUNDS | ELI LILLY AND COMPANY | 2016-09-01 | — | — | US | disclosed |
| US-20160251306-A1 | DIMETHYLBENZOIC ACID COMPOUNDS | ELI LILLY AND COMPANY | 2016-09-01 | — | — | US | disclosed |
| US-20160251306-A1 | DIMETHYLBENZOIC ACID COMPOUNDS | ELI LILLY AND COMPANY | 2016-09-01 | — | — | US | disclosed |
| CN-105793236-A | Dimethylbenzoic acid compound | 伊莱利利公司 | 2016-07-20 | — | — | CN | disclosed |
| WO-2015094912-A1 | DIMETHYLBENZOIC ACID COMPOUNDS | ELI LILLY AND COMPANY (US) | 2015-06-25 | — | — | WO | disclosed |
| EP-0369208-B1 | PROCESS FOR THE PREPARATION OF 3,5-DIMETHYL-4-METHOXY PYRIDINE DERIVATIVES, AND INTERMEDIATE THEREFOR | Hafslund Nycomed Pharma Aktiengesellschaft (AT) | 1993-03-17 | — | — | EP | disclosed |
| US-5066810-A | 3,5-DIMETHYL-4-METHOXYPYRIDINE DERIVATIVES | CL PHARMA AKTIENGESELLSCHAFT (AT) | 1991-11-19 | — | — | US | disclosed |
| JP-H03215472-A | NOVEL 4-SUBSTITUTED-3,5-DIMETHYLPICOLINIC ACID COMPOUND AND ITS PRODUCTION | TOKYO TANABE CO LTD | 1991-09-20 | — | — | JP | disclosed |
| EP-0369208-A1 | Process for the preparation of 3,5-dimethyl-4-methoxy pyridine derivatives, and intermediate therefor | Hafslund Nycomed Pharma Aktiengesellschaft (AT) | 1990-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005721-B2 | Dimethylbenzoic acid compounds | PTGER4, EDNRB, EPB41 | ALDH1A1 272/4885TDP1 4081/4885MEN1 2770/4885 |
| US-20160251306-A1 | DIMETHYLBENZOIC ACID COMPOUNDS | PTGER4, EDNRB, EPB41 | ALDH1A1 272/4885TDP1 4081/4885MEN1 2770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.