Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 9/20 | 0.79 |
| ▸ | EDNRB | P24530 | 8/20 | 0.79 |
| ▸ | KDM1A | O60341 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046446 | 0.92 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL9045018 | 0.89 | EDNRA (1.00) | EDNRAEDNRBKDM1A | |
| SCHEMBL9044584 | 0.89 | EDNRA (1.00) | EDNRAEDNRBKDM1A | |
| SCHEMBL9045132 | 0.88 | EDNRA (0.98) | EDNRAEDNRBKDM1A | |
| SCHEMBL9044911 | 0.85 | EDNRA (0.76) | EDNRAEDNRBCCR2 | |
| SCHEMBL9046659 | 0.85 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL9044916 | 0.85 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL9046653 | 0.85 | EDNRA (0.76) | EDNRAEDNRB | |
| SCHEMBL9492250 | 0.84 | KDM1A (0.59) | EDNRAEDNRBKDM1AMEN1KMT2A | |
| SCHEMBL9046971 | 0.83 | EDNRA (0.90) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270313-A | Treatment of circulatory disorders | HOFFMANN-LA ROCHE INC. (US) | 1993-12-14 | — | — | US | disclosed |