Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24854772 | 0.98 | ACHE (0.50) | ACHEL3MBTL1LMNASMN1; SMN2EPHX2 | |
| SCHEMBL11141024 | 0.94 | ACHE (0.52) | ACHEL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9494464 | 0.89 | ACHE (0.58) | ACHE | |
| SCHEMBL9494648 | 0.89 | ACHE (0.58) | ACHE | |
| SCHEMBL14094998 | 0.88 | ACHE (0.57) | ACHELMNASMN1; SMN2EPHX2 | |
| SCHEMBL27357778 | 0.88 | ACHE (0.47) | ACHEL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL27357775 | 0.88 | ACHE (0.47) | ACHEL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL26460411 | 0.88 | ACHE (0.47) | ACHEL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9495238 | 0.88 | ACHE (0.50) | ACHEL3MBTL1LMNASMN1; SMN2EPHX2 | |
| SCHEMBL22138601 | 0.86 | ACHE (0.46) | ACHEL3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073622-A2 | RADIOPHARMACEUTICAL COMPOSITIONS TARGETING EPHRIN TYPE-A RECEPTOR 2 AND USES THEREOF | RAYZEBIO, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
| WO-2023014979-A9 | CONJUGATES COMPRISING COVALENT BINDERS FOR TARGETING INTRACELLULAR KRAS G12C PROTEINS | RAYZEBIO, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023014979-A1 | CONJUGATES COMPRISING COVALENT BINDERS FOR TARGETING INTRACELLULAR KRAS G12C PROTEINS | RAYZEBIO, INC. (US) | 2023-02-09 | — | — | WO | disclosed |
| US-5179223-A | Reacting primary amine, urea and oxime | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |