SCHEMBL9494010

SCHEMBL9494010

CC(O)C(C)(O)c1cccnc1

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 4/20 0.49
KCNH2 Q12809 1/20 0.49
CYP19A1 P11511 4/20 0.49
CYP3A4 P08684 3/20 0.49
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP11B1 P15538 1/20 0.49
CYP11B2 P19099 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
CYP3A5 P20815 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12238648 0.89 CYP3A4 (0.49) KCNA5KCNH2CYP19A1CYP3A4LMNA
SCHEMBL9547408 0.79 CYP19A1 (0.55) KCNA5CYP19A1CYP3A4LMNACYP1A2
SCHEMBL3021832 0.79 CYP19A1 (0.55) KCNA5CYP19A1CYP3A4LMNACYP1A2
SCHEMBL29896215 0.79 CYP19A1 (0.55) KCNA5CYP19A1CYP3A4LMNACYP1A2
SCHEMBL2423712 0.79 CYP19A1 (0.55) KCNA5CYP19A1CYP3A4LMNACYP1A2
SCHEMBL1375896 0.79 CYP19A1 (0.55) KCNA5CYP19A1CYP3A4LMNACYP1A2
SCHEMBL11630827 0.78 KCNA5 (0.49) KCNA5KCNH2CYP19A1CYP3A4LMNA
SCHEMBL20148789 0.78 CYP3A4 (0.62) KCNA5KCNH2CYP19A1CYP3A4CYP3A5
SCHEMBL18779167 0.78 KCNA5 (0.47) KCNA5KCNH2CYP19A1CYP3A4LMNA
SCHEMBL17974007 0.78 CYP3A4 (0.46) KCNA5KCNH2CYP19A1CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0531408-A1 ELECTROCHEMICAL SYNTHESIS AND SIMULTANEOUS PURIFICATION PROCESS REILLY INDUSTRIES, INC. (US) 1993-03-17 EP claimed
US-5074974-A Ion exchanging REILLY INDUSTRIES, INC. (US) 1991-12-24 US claimed
WO-1991019020-A2 ELECTROCHEMICAL SYNTHESIS AND SIMULTANEOUS PURIFICATION PROCESS REILLY NDUSTRIES, INC. (US) 1991-12-12 WO claimed