Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL373166 | 0.67 | HSP90AA1 (0.50) | HSP90AA1 | |
| SCHEMBL11100796 | 0.67 | HSP90AA1 (0.52) | HSP90AA1 | |
| SCHEMBL5907860 | 0.65 | HSP90AA1 (0.57) | HSP90AA1 | |
| Hydrochloric Acid SCHEMBL4760945 | 0.65 | HSP90AA1 (0.47) | HSP90AA1 | |
| SCHEMBL22229463 | 0.64 | HSP90AA1 (0.40) | HSP90AA1 | |
| SCHEMBL3804688 | 0.63 | DGAT1 (0.47) | HSP90AA1 | |
| SCHEMBL13911007 | 0.62 | HSP90AA1 (0.44) | HSP90AA1 | |
| SCHEMBL4458 | 0.62 | — | — | |
| SCHEMBL1923146 | 0.62 | — | — | |
| SCHEMBL9704689 | 0.62 | HSP90AA1 (0.46) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451802-A1 | PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES AND THEIR USE IN CANCER THERAPY | Pathway Therapeutics, Inc. (US) | 2012-05-16 | — | — | EP | claimed |
| WO-2011005119-A1 | PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES AND THEIR USE IN CANCER THERAPY | PATHWAY THERAPEUTICS LIMITED (NZ) | 2011-01-13 | — | — | WO | claimed |
| EP-2451802-A1 | PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES AND THEIR USE IN CANCER THERAPY | Pathway Therapeutics, Inc. (US) | 2012-05-16 | — | — | EP | disclosed |
| WO-2011005119-A1 | PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES AND THEIR USE IN CANCER THERAPY | PATHWAY THERAPEUTICS LIMITED (NZ) | 2011-01-13 | — | — | WO | disclosed |