Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935760 | 0.98 | ALDH1A1 (0.59) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL30526531 | 0.98 | ALDH1A1 (0.59) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL28046865 | 0.98 | ALDH1A1 (0.59) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27949512 | 0.97 | ALDH1A1 (0.58) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL9499276 | 0.95 | KMT2A (0.62) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL9495199 | 0.88 | ALDH1A1 (0.61) | TP53ALDH1A1KMT2AMEN1LMNA | |
| Hydrochloric Acid SCHEMBL27388065 | 0.87 | ALDH1A1 (0.60) | TP53ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL25676025 | 0.84 | ALDH1A1 (0.54) | TP53ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL27782199 | 0.84 | ALDH1A1 (0.54) | TP53ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL13685794 | 0.83 | ALDH1A1 (0.69) | TSHRTP53CYP3A4MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0120359-A1 | Tetrahydrothiophenone derivative active in respiratory system affections | YASON S.r.l (IT) | 1984-10-03 | — | — | EP | claimed |
| EP-0267794-B1 | PROCESS FOR PREPARING POLYOLEFINS | Nippon Petrochemicals Co., Ltd. (JP) | 1993-05-05 | — | — | EP | disclosed |
| EP-0267794-A2 | Process for preparing polyolefins | Nippon Petrochemicals Co., Ltd. (JP) | 1988-05-18 | — | — | EP | disclosed |
| US-4525555-A | TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS | NIPPON OIL COMPANY, LIMITED (JP) | 1985-06-25 | — | — | US | disclosed |