SCHEMBL9494181

SCHEMBL9494181

CCCC(CC(C)(C)C)=NO

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13317699 1.00 HDAC3 (0.33) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL758250 0.78
SCHEMBL10775786 0.75 ALDH1A1 (0.35) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL13317236 0.75 HDAC3 (0.30) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL9005200 0.73
SCHEMBL640375 0.73
SCHEMBL640374 0.73
SCHEMBL13318091 0.72
SCHEMBL13317239 0.72
SCHEMBL647557 0.70 HDAC3 (0.32) HDAC3HDAC1HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0535057-A1 PROCESS FOR THE PREPARATION OF KETOXIMES EASTMAN CHEMICAL COMPANY (US) 1993-04-07 EP claimed
WO-1991018867-A1 PROCESS FOR THE PREPARATION OF KETOXIMES EASTMAN KODAK COMPANY (US) 1991-12-12 WO claimed