Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899555 | 0.87 | KDM4E (0.47) | GAKKDM4ESORT1CYP1A2 | |
| SCHEMBL29588619 | 0.83 | CYP1A2 (0.56) | GAKKDM4ECCNE2CCNA2CCNE1 | |
| SCHEMBL19983427 | 0.83 | CYP1A2 (0.56) | GAKKDM4ECCNE2CCNA2CCNE1 | |
| SCHEMBL2712104 | 0.81 | KDM4E (0.49) | KDM4ECCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL5101813 | 0.80 | LMNA (0.62) | GAKCCNE2CCNA2CCNE1CDK2 | |
| SCHEMBL12033714 | 0.80 | KDM4E (0.47) | GAKKDM4ECCNE2CCNA2CCNE1 | |
| SCHEMBL437638 | 0.80 | MCHR1 (0.59) | GAKMCHR1BACE1 | |
| SCHEMBL21173342 | 0.78 | GAK (0.48) | GAKKDM4ECCNE2CCNA2CCNE1 | |
| SCHEMBL3906125 | 0.77 | GAA (0.47) | KDM4EDHODHCYP1A2 | |
| SCHEMBL3760247 | 0.77 | LMNA (0.61) | KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113432-B1 | CHLOROMETHYL QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | ALKALOIDA VEGYéSZETI GYáR (HU) | 1993-03-17 | — | — | EP | disclosed |
| EP-0113432-A1 | Chloromethyl quinoline derivatives, process for their preparation and their use | ALKALOIDA VEGYéSZETI GYáR (HU) | 1984-07-18 | — | — | EP | disclosed |