Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.77 |
| ▸ | ATM | Q13315 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494805 | 0.91 | TSHR (0.59) | TSHRCYP3A4MAPK1ATML3MBTL1 | |
| Dichlorodiphenyldichloroethylene SCHEMBL177472 | 0.88 | TSHR (1.00) | TSHRCYP3A4MAPK1ATML3MBTL1 | |
| SCHEMBL9494935 | 0.80 | MEN1 (0.48) | TSHRCYP3A4MAPK1ATML3MBTL1 | |
| SCHEMBL9493837 | 0.80 | MEN1 (0.48) | TSHRCYP3A4MAPK1ATML3MBTL1 | |
| SCHEMBL7772998 | 0.79 | TSHR (0.81) | TSHRCYP3A4MAPK1ATML3MBTL1 | |
| SCHEMBL9495925 | 0.77 | TSHR (0.77) | TSHRCYP3A4MAPK1ATML3MBTL1 | |
| SCHEMBL9494307 | 0.77 | TSHR (0.77) | TSHRCYP3A4MAPK1ATML3MBTL1 | |
| SCHEMBL197605 | 0.77 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL10839178 | 0.77 | CYP2A6 (0.61) | TSHRMAPK1KMT2AMEN1ALDH1A1 | |
| Methyl Alcohol SCHEMBL27601464 | 0.75 | CYP2A6 (0.50) | TSHRKMT2AMEN1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352956-B1 | PROCESS FOR THE PRODUCTION OF HALOBENZOPHENONE DERIVATIVES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-4960945-A | Process for the production of halobenzophenone derivatives | KUREHA KAGAKU KOGYO K.K. (JP) | 1990-10-02 | — | — | US | disclosed |
| EP-0352956-A1 | Process for the production of halobenzophenone derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-31 | — | — | EP | disclosed |