SCHEMBL9494935

SCHEMBL9494935

Fc1ccc(C(=C(Cl)Cl)c2ccc(Br)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
MAPK1 P28482 2/20 0.48
CYP3A4 P08684 2/20 0.48
TSHR P16473 1/20 0.48
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 2/20 0.42
CTSL P07711 1/20 0.42
STAT1 P42224 1/20 0.41
CYP1A2 P05177 1/20 0.41
POLB P06746 1/20 0.41
CYP2D6 P10635 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CES2 O00748 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7938527 0.89 MEN1 (0.59) MEN1KMT2AMAPK1CYP3A4TSHR
SCHEMBL9494805 0.89 TSHR (0.59) MEN1KMT2AMAPK1CYP3A4TSHR
SCHEMBL9495925 0.80 TSHR (0.77) MEN1KMT2AMAPK1CYP3A4TSHR
SCHEMBL9494493 0.80 TSHR (0.77) MEN1KMT2AMAPK1CYP3A4TSHR
SCHEMBL9493837 0.78 MEN1 (0.48) MEN1KMT2AMAPK1CYP3A4TSHR
SCHEMBL9495547 0.78 MEN1 (0.48) MEN1KMT2AMAPK1CYP3A4TSHR
SCHEMBL29525203 0.75
SCHEMBL7026005 0.75
SCHEMBL1622 0.75
Methyl Alcohol SCHEMBL28191829 0.73 SMN1; SMN2 (0.54) MEN1KMT2AMAPK1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0352956-B1 PROCESS FOR THE PRODUCTION OF HALOBENZOPHENONE DERIVATIVES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-03-17 EP disclosed
US-4960945-A Process for the production of halobenzophenone derivatives KUREHA KAGAKU KOGYO K.K. (JP) 1990-10-02 US disclosed
EP-0352956-A1 Process for the production of halobenzophenone derivatives KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-01-31 EP disclosed