Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 8/20 | 0.37 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 2/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL110296 | 0.79 | SLC7A5 (0.58) | SLC7A5STAT3GABRA1GABRG2GABRB3 | |
| SCHEMBL5047980 | 0.78 | LOXL2 (0.33) | LOXL2 | |
| SCHEMBL6754862 | 0.78 | MAPK1 (0.46) | F2 | |
| SCHEMBL28350987 | 0.77 | SLC7A5 (0.56) | SLC7A5STAT3GABRA1GABRG2GABRB3 | |
| Water SCHEMBL28897664 | 0.77 | SLC7A5 (0.56) | SLC7A5STAT3GABRA1GABRG2GABRB3 | |
| Hydrogen Peroxide SCHEMBL27146001 | 0.77 | SLC7A5 (0.60) | SLC7A5F2STAT3GABRA1GABRG2 | |
| SCHEMBL4901667 | 0.75 | SLC7A5 (0.52) | SLC7A5F2TMPRSS6STAT3 | |
| Adipic Acid SCHEMBL27893785 | 0.74 | SLC7A5 (0.55) | SLC7A5F2STAT3GABRA1GABRG2 | |
| SCHEMBL1839768 | 0.74 | GAA (0.36) | F2TMPRSS6 | |
| SCHEMBL40750 | 0.73 | SLC7A5 (0.56) | SLC7A5STAT3ABCB1ABCG2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185433-A | Cross-linking protein compositions having two or more identical binding sites | CENTOCOR, INC. (US) | 1993-02-09 | — | — | US | disclosed |
| US-5144043-A | Coupling protein or peptide to radionucleotide; labeling antibodies | CENTOCOR (US) | 1992-09-01 | — | — | US | disclosed |