⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19455 | 0.93 | — | — | |
| SCHEMBL3692762 | 0.93 | NCF1 (0.48) | — | |
| SCHEMBL9630437 | 0.90 | — | — | |
| SCHEMBL3058521 | 0.90 | PLG (0.48) | — | |
| Hydrochloric Acid SCHEMBL17446 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL15648007 | 0.87 | — | — | |
| SCHEMBL27810 | 0.86 | — | — | |
| Oxalic Acid SCHEMBL9779892 | 0.84 | PLG (0.52) | — | |
| SCHEMBL3536114 | 0.83 | CYP2D6 (0.54) | — | |
| SCHEMBL13893972 | 0.83 | CYP2D6 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324154-B1 | 1,2 BIS(AMINOMETHYL)CYCLOBUTANE-PLATINUM-COMPLEXES | ASTA Medica Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | claimed |
| EP-0482172-A1 | ANTI-TUMOR AGENTS HAVING REDUCED TOXICITY ON THE BASIS OF CYTOSTATIC AGENTS AND XANTHOGENATES | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 1992-04-29 | — | — | EP | claimed |
| WO-1991017757-A1 | ANTI-TUMOR AGENTS HAVING REDUCED TOXICITY ON THE BASIS OF CYTOSTATIC AGENTS AND XANTHOGENATES | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 1991-11-28 | — | — | WO | claimed |
| US-5023335-A | Antitumor agents | ASTA PHARMA AKTIENGESELLSCHAFT | 1991-06-11 | — | — | US | claimed |
| EP-0482172-A1 | ANTI-TUMOR AGENTS HAVING REDUCED TOXICITY ON THE BASIS OF CYTOSTATIC AGENTS AND XANTHOGENATES | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 1992-04-29 | — | — | EP | disclosed |
| WO-1991017757-A1 | ANTI-TUMOR AGENTS HAVING REDUCED TOXICITY ON THE BASIS OF CYTOSTATIC AGENTS AND XANTHOGENATES | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 1991-11-28 | — | — | WO | disclosed |
| US-5023335-A | Antitumor agents | ASTA PHARMA AKTIENGESELLSCHAFT | 1991-06-11 | — | — | US | disclosed |
| US-5023335-A | Antitumor agents | ASTA PHARMA AKTIENGESELLSCHAFT | 1991-06-11 | — | — | US | disclosed |