Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 known ✓ | P22894 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104641 | 0.94 | — | — | |
| Alcohol SCHEMBL8816286 | 0.77 | TSHR (0.39) | TSHRALDH1A1MMP8 | |
| SCHEMBL4234783 | 0.76 | TSHR (0.32) | TSHR | |
| SCHEMBL3629795 | 0.75 | LMNA (0.34) | TSHRALDH1A1 | |
| Alcohol SCHEMBL4771437 | 0.75 | TSHR (0.50) | TSHRALDH1A1 | |
| SCHEMBL13249198 | 0.75 | TSHR (0.31) | TSHR | |
| SCHEMBL8528537 | 0.74 | — | — | |
| SCHEMBL17994854 | 0.74 | — | — | |
| SCHEMBL100229 | 0.73 | — | — | |
| SCHEMBL28693585 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0317975-B1 | PROCESS FOR THE PRODUCTION OF SATURATED NEO-ALCOHOLS | UNION CARBIDE CORPORATION (US) | 1993-04-28 | — | — | EP | claimed |