SCHEMBL9495069

SCHEMBL9495069

CC(=O)N(C(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C)[C@H](C=O)CCCCN

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 4/20 0.38
ERAP2 Q6P179 3/20 0.37
ERAP1 Q9NZ08 2/20 0.37
LNPEP Q9UIQ6 2/20 0.37
DPP8 Q6V1X1 2/20 0.36
DPP9 Q86TI2 2/20 0.36
DPP7 Q9UHL4 2/20 0.36
FURIN P09958 1/20 0.33
PCSK6 P29122 1/20 0.33
PSMB5 P28074 1/20 0.33
PSMB2 P49721 1/20 0.33
CPB2 Q96IY4 3/20 0.32
DPP4 P27487 1/20 0.32
NMT2 O60551 1/20 0.32
NMT1 P30419 1/20 0.32
NPY4R P50391 4/20 0.32
NPY1R P25929 3/20 0.32
NPY2R P49146 3/20 0.32
NPY5R Q15761 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1683232 0.90 DPP7 (0.38) DPP8DPP9DPP7DPP4
SCHEMBL3035816 0.88 FURIN (0.36) OPRK1ERAP2ERAP1LNPEPDPP8
SCHEMBL7039378 0.87 SCN9A (0.32) DPP8DPP9DPP7DPP4
SCHEMBL7757841 0.84 FOLH1 (0.35)
SCHEMBL2782827 0.84 NPY4R (0.46) NPY4RNPY1RNPY2RNPY5R
SCHEMBL11596017 0.84 NPY4R (0.46) NPY4RNPY1RNPY2RNPY5R
Hydrochloric Acid SCHEMBL11596923 0.83 NPY4R (0.45) NPY4RNPY1RNPY2RNPY5R
SCHEMBL10936285 0.74 NPY4R (0.43) NPY4RNPY1RNPY2RNPY5R
SCHEMBL16565945 0.74 CTSK (0.45) ERAP2ERAP1LNPEPDPP8DPP9
Hydrochloric Acid SCHEMBL11300702 0.74 NPY4R (0.42) NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0313969-B1 TRIPEPTIDE DERIVATIVES AND ANTIPLASMIN AGENTS CONTAINING THE SAME NITTO BOSEKI CO., LTD. (JP) 1993-03-24 EP disclosed
US-4883863-A FROM LYSINE OR TYROSINE, PHENYLALANINE AND LYSINE, HEMOSTATIC AGENTS NITTO BOSEKI CO., LTD. (JP) 1989-11-28 US disclosed
EP-0313969-A2 Tripeptide derivatives and antiplasmin agents containing the same NITTO BOSEKI CO., LTD. (JP) 1989-05-03 EP disclosed