Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28377962 | 0.81 | CHRM1 (0.45) | CHRM1BCHEEPHX1 | |
| SCHEMBL10810342 | 0.79 | EPHX1 (0.47) | CHRM1BCHESMN1; SMN2EPHX1 | |
| SCHEMBL103736 | 0.79 | — | — | |
| SCHEMBL19571000 | 0.78 | CHRM1 (0.50) | CHRM1BCHELMNASMN1; SMN2EPHX1 | |
| SCHEMBL21828117 | 0.78 | CHRM1 (0.46) | CHRM1BCHEEPHX1 | |
| SCHEMBL19571012 | 0.78 | CHRM1 (0.50) | CHRM1BCHELMNASMN1; SMN2EPHX1 | |
| SCHEMBL19571009 | 0.78 | CHRM1 (0.50) | CHRM1BCHELMNASMN1; SMN2EPHX1 | |
| SCHEMBL19570999 | 0.78 | CHRM1 (0.50) | CHRM1BCHELMNASMN1; SMN2EPHX1 | |
| SCHEMBL19571013 | 0.78 | CHRM1 (0.50) | CHRM1BCHELMNASMN1; SMN2EPHX1 | |
| Hydrochloric Acid SCHEMBL28974203 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324154-B1 | 1,2 BIS(AMINOMETHYL)CYCLOBUTANE-PLATINUM-COMPLEXES | ASTA Medica Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |