Iodide

Iodide

SCHEMBL9495385

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C)cc2)cc1.I

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 6/20 0.53
ALDH1A1 P00352 6/20 0.58
TSHR P16473 4/20 0.58
TDP1 Q9NUW8 2/20 0.53
CA2 P00918 2/20 0.41
LPL P06858 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
MAPT P10636 2/20 0.41
CYP2C19 P33261 2/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
CA1 P00915 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CHRNA7 P36544 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16982395 0.97 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1CA2
SCHEMBL6123161 0.97 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1CA2
SCHEMBL4893877 0.97 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1CA2
SCHEMBL7486403 0.97 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1CA2
SCHEMBL76680 0.97 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1CA2
SCHEMBL12240222 0.97 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1CA2
SCHEMBL615437 0.97 ALDH1A1 (0.61) ALDH1A1TSHRACHETDP1CA2
Hydrochloric Acid SCHEMBL25295730 0.93 ALDH1A1 (0.58) ALDH1A1TSHRACHETDP1CA2
Ammonia Solution, Strong SCHEMBL8759606 0.93 ALDH1A1 (0.58) ALDH1A1TSHRACHETDP1CA2
Hydrochloric Acid SCHEMBL8469549 0.90 ALDH1A1 (0.55) ALDH1A1TSHRACHETDP1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119505867-A Gold nanocluster and application thereof in organophosphorus pesticide residue detection 河南省农业科学院农产品质量安全研究所 2025-02-25 CN disclosed
EP-0283586-B1 HOMOLOGATION PROCESS UNION CARBIDE CORPORATION (US) 1993-03-17 EP disclosed
US-5026907-A High efficiency, selectivity with lithium, sodium or potassium iodide combined with phophorous ligand of complex; reacting alcohol, ester and carbon monoxide UNION CARBIDE CHEMICALS AND PLASTICS TECHNOLOGY CORPORATION (US) 1991-06-25 US disclosed
US-4990654-A Reacting mixture of methanol and ethanol with carbon monoxide using halogen-promoted phosphorus-containing catalyst system UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1991-02-05 US disclosed
US-4927967-A Production of carboxylic acids from organic formate esters using rhodium complex catalysts UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1990-05-22 US disclosed
EP-0173170-B1 PROCESS FOR THE PREPARATION OF ANHYDROUS CARBOXYLIC ACIDS FROM ALCOHOLS UNION CARBIDE CORPORATION (US) 1989-09-20 EP disclosed
EP-0283586-A2 Homologation process UNION CARBIDE CORPORATION (US) 1988-09-28 EP disclosed
EP-0171802-B1 PRODUCTION OF CARBOXYLIC ANHYDRIDES FROM METHYL CARBOXYLATES USING RHODIUM COMPLEX CATALYSTS UNION CARBIDE CORPORATION (US) 1988-04-06 EP disclosed
US-4727200-A RHODIUM-BASED CATALYST; MILD CONDITIONS UNION CARBIDE CORPORATION (US) 1988-02-23 US disclosed
EP-0171652-B1 PRODUCTION OF CARBOXYLIC ACIDS FROM ALCOHOLS USING RHODIUM COMPLEX CATALYSTS UNION CARBIDE CORPORATION (US) 1988-01-27 EP disclosed
EP-0171652-A1 Production of carboxylic acids from alcohols using rhodium complex catalysts UNION CARBIDE CORPORATION (US) 1986-02-19 EP disclosed
EP-0171804-A2 Production of acetate esters from alcohols using rhodium complex catalysts UNION CARBIDE CORPORATION (US) 1986-02-19 EP disclosed
EP-0171651-A1 Production of carboxylic acids from organic formates using rhodium complex catalysts UNION CARBIDE CORPORATION (US) 1986-02-19 EP disclosed
EP-0171802-A1 Production of carboxylic anhydrides from methyl carboxylates using rhodium complex catalysts UNION CARBIDE CORPORATION (US) 1986-02-19 EP disclosed
WO-1986000889-A1 PRODUCTION OF CARBOXYLIC ACIDS FROM ORGANIC FORMATE ESTERS USING RHODIUM COMPLEX CATALYSTS UNION CARBIDE CORPORATION (US) 1986-02-13 WO disclosed
WO-1986000888-A1 PRODUCTION OF CARBOXYLIC ACIDS FROM ALCOHOLS USING RHODIUM COMPLEX CATALYSTS UNION CARBIDE CORPORATION (US) 1986-02-13 WO disclosed
US-4563309-A CARBONYLATION UNION CARBIDE CORPORATION (US) 1986-01-07 US disclosed
US-4490559-A SYNTHESIS GAS AND A GROUP VII COMPOUND CATALYST SHELL OIL COMPANY (US) 1984-12-25 US disclosed
US-4447648-A USING SYNTHESIS GAS AND A GROUP VIII COMPOUND UNION CARBIDE CORPORATION (US) 1984-05-08 US disclosed
US-4429165-A TRIVALENT ORGANOPHOSPHORUS AND ORGANONITROGEN COMPOUNDS AS PROMOTERS UNION CARBIDE CORPORATION (US) 1984-01-31 US disclosed