Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.53 |
| ▸ | RARB | P10826 | 3/20 | 0.53 |
| ▸ | RARG | P13631 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | GOT1 | P17174 | 1/20 | 0.52 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5078203 | 0.90 | RARA (0.65) | RARARARBRARGLMNAKMT2A | |
| SCHEMBL9737080 | 0.90 | RARA (0.53) | RARARARBRARGLMNAKMT2A | |
| SCHEMBL8521998 | 0.90 | RARA (0.53) | RARARARBRARGLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL9737093 | 0.89 | RARA (0.64) | RARARARBRARGLMNAKMT2A | |
| SCHEMBL9492199 | 0.89 | RARA (0.53) | RARARARBRARGLMNAKMT2A | |
| SCHEMBL8523165 | 0.89 | RARA (0.57) | RARARARBRARGLMNAKMT2A | |
| SCHEMBL9493337 | 0.85 | RARA (0.49) | RARARARBRARGLMNAKMT2A | |
| SCHEMBL9492316 | 0.84 | RARA (0.48) | RARARARBRARGLMNAKMT2A | |
| SCHEMBL9499636 | 0.83 | RARA (0.48) | RARARARBRARGLMNAKMT2A | |
| SCHEMBL9493293 | 0.82 | KMT2A (0.56) | RARARARBRARGLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325540-B1 | AROMATIC ESTERS AND THIOESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN OR ANIMAL THERAPEUTICS AND IN COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1993-04-14 | — | — | EP | claimed |
| EP-0325540-A1 | Aromatic esters and thioesters, process for their preparation and their use in human or animal therapeutics and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1989-07-26 | — | — | EP | claimed |
| EP-0325540-B1 | AROMATIC ESTERS AND THIOESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN OR ANIMAL THERAPEUTICS AND IN COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1993-04-14 | — | — | EP | disclosed |
| US-5173289-A | Skin disorders, antiinflammatory agents | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1992-12-22 | — | — | US | disclosed |
| US-4925658-A | TREATMENT OF DERMATOLOGIC, RHEUMATIC, RESPIRATORY, OPHTHALMOLOGIC DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES (CIRD) (FR) | 1990-05-15 | — | — | US | disclosed |
| EP-0325540-A1 | Aromatic esters and thioesters, process for their preparation and their use in human or animal therapeutics and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1989-07-26 | — | — | EP | disclosed |