Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | CDC25B | P30305 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25C | P30307 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15353454 | 0.84 | TSHR (0.45) | TSHRCDC25BALDH1A1HSD17B10KDM4E | |
| SCHEMBL29599494 | 0.82 | TSHR (0.46) | TSHRALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL826816 | 0.82 | TSHR (0.46) | TSHRALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL21494809 | 0.81 | ADRA2A (0.37) | TSHRCDC25BALDH1A1HSD17B10KDM4E | |
| SCHEMBL23459940 | 0.80 | CA12 (0.50) | TSHRALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL9150759 | 0.79 | TSHR (0.73) | TSHRCDC25BALDH1A1HSD17B10KDM4E | |
| SCHEMBL9494725 | 0.79 | TSHR (0.58) | TSHRCDC25BALDH1A1HSD17B10KDM4E | |
| SCHEMBL6777873 | 0.79 | CA12 (0.45) | TSHRALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL6337807 | 0.79 | CNR2 (0.41) | HPGDCYP1A2POLBCYP3A4GAA | |
| SCHEMBL28967942 | 0.78 | CNR2 (0.40) | ALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267794-B1 | PROCESS FOR PREPARING POLYOLEFINS | Nippon Petrochemicals Co., Ltd. (JP) | 1993-05-05 | — | — | EP | disclosed |
| EP-0267794-A2 | Process for preparing polyolefins | Nippon Petrochemicals Co., Ltd. (JP) | 1988-05-18 | — | — | EP | disclosed |